WASHINGTON - President-elect Barack Obama said Wednesday that Al-Qaeda and Osama bin Laden remain the "number one threat" to US security, after the militant leader called on Muslims to launch a jihad against Israel for its aggression in Gaza. In a new audio commentary, Osama bin Laden also warned of new fronts in his war on the West. "I haven't changed my mind, that bin Laden and Al Qaeda are our number one threat when it comes to American security," Obama told reporters Wednesday after a new voice recording emerged from the networks' leader. The 22-minute audio recording, which the US-based Site Intelligence Group said it believes is authentic, was the first commentary from the Al-Qaeda leader in last eight months. The White House declined to immediately authenticate the statement. But spokesman Gordon Johndroe said: "It appears this tape demonstrates his isolation and continued attempts to remain relevant at a time when Al-Qaeda's ideology, mission, and agenda are being questioned and challenged throughout the world." Obama's comments came at a joint press conference with his vice president-elect, Joe Biden, along with the Republican senator, Lindsey Graham. Both Graham and Biden returned on Tuesday from a visit to Afghanistan, Pakistan and Iraq. Obama emphasised the need for a regional approach to resolve the Afghanistan problem. He also signaled his resolve to forge a closer American cooperation with Pakistan towards dealing with the problem of violent extremism. "As Joe (Biden) indicated, we have to take a regional approach. We're not going to solve the problem just in Afghanistan; we're going to have address issues in Pakistan as well," Obama said adding that he would have more to say on this issue after being sworn in on January 20. His administration, working in concert with Congress, with Republicans and with the American people, Obama said: "We're going to do everything in our power to make sure that they cannot create safe havens they can attack America. That's the bottom line." Terming Pakistan a determining factor in the success of the US-led war against terrorism in Afghanistan, vice president-elect Joe Biden said he expected things would be getting tougher before becoming better in Afghanistan. Referring to the speeches made by him and the president-elect, Barack Obama, during election campaign days last year, Biden said there would be major change in Afghan policy. "Pakistan's position on Afghanistan is going to affect our ability to succeed in Afghanistan," Biden, who went to the region in his capacity as a senator and outgoing chairman of the Senate Foreign Relations Committee, said. During his stay in Pakistan, Biden met the top Pakistani leadership, and officials from its military and intelligence. "There is about to become a shift, which you have all known and talked about, we've mentioned it in the campaign, and that is that there need to be more resources to attend to the situation in Afghanistan, which has deteriorated over the last six years. It has not gotten better," he said. Supporting new Administration's plan to send additional 35,000 troops to Afghanistan, Senator Lindsey Graham said that focus was diverted to Iraq and there is now need to reengage. Graham said reengagement in Afghanistan now is going to come at a heavy price. "I would like every American to know that not only are the troops needed; unfortunately, casualties are likely to increase. But we have a game plan in Afghanistan that I think justifies the expenditures of blood and treasure that's about to come," he said. APP adds: President-elect Barack Obama has expressed his resolve to forge a closer American cooperation with Pakistan to deal with the problem of extremism along Pak-Afghan border as part of regional approach that his administration intends to pursue after taking charge next week. Interacting with the media upon Vice President-elect Joseph Biden's return from a visit to Afghanistan, Pakistan and Iraq, Obama described Al-Qaeda as biggest threat for the United States. "As Joe Biden indicated, we have to take a regional approach, we are not going to solve the problem just in Afghanistan, we are going to address issues in Pakistan as well," said Obama, who will take oath as US President on Tuesday (January 20). To a question, Obama said "Osama Bin Laden and Al-Qaeda are our No one threat when it comes to the US security." "And our administration working in concert with Congress, with Republicans, and with the US people, we are going to do everything in our power to make sure that they cannot create safe havens to attack the US. That is the bottom line," the president-elect added. Obama would not elaborate his remarks, saying the US has one president at a time, but said he would spell out particulars of his administration's policy toward the region immediately after assuming his office. Biden was confident of prospects of progress in the region. "I have been encouraged by the trip, the assets we have in place, the progress and cooperation that is incrementally occurring, I have come more encouraged. I think you will have the assets to increase the prospects of success." Biden said he undertook the visit to Pakistan, Afghanistan and Iraq at the behest of the president-elect "with the said purpose of assessing the situation on ground, to determine what the situation was, what the problems were," and report back to Obama for way forward. The vice-president elect, who met with top political leaders in Islamabad including President Asif Ali Zardari and Prime Minister Yousuf Raza Gilani as well as senior military leaders, acknowledged the Pakistan's importance vis-a-vis peace and security efforts, saying "Pakistan's position on Afghanistan is going to affect our ability to succeed in Afghanistan." He underlined the need for building political institutions in all three countries and said focus on personalities is not the answer to problems. "There is a need to build institutions, political institutions that are sustainable in each of the three countries. He said we conveyed that notion to each of the countries in question. And they all had slightly different and significant different problems." Speaking in a broader perspective, he said success in each of the countries affects the prospects of success in that region. Biden also told newsmen that the bipartisan delegation "went to listen, not to convey policy, as the president-elect has stated, we have one president at a time." "And so, I made it very clear in speaking with every leader literally we met with in each of the three countries, military as well as civilian, I made it absolutely clear that I was not there to make policy, I was there to listen but to listen and occasionally express concern about some of their actions or lack of actions." On Afghanistan, he said, there is going to be a 'significant shift' in the form of 35,000 troops deployment in the insurgency-hit country, where the situation has deteriorated over the several years. "Things are going to get tougher in Afghanistan before they get better." He described the Congressional delegation's visit to the region as 'very worthwhile' while Obama said the lawmakers' recommendations would be of great help to him. "The recommendations that you're going to be delivering to me are going to be of enormous help in making sure that we do what is my No 1 task as president-elect and as president, and that is to keep the American people safe and to make sure that when we deploy our military, that we do so with a clear sense of mission and with strong support from the American people," Obama stated.