KARACHI - The fatal Kawasaki disease, also known as lymph node syndrome, occurs first time in the metropolis as three cases of the disease were reported at Aga Khan University Hospital (AKUH) Karachi. Three patients were admitted to the AKUH with the symptoms of persistent fever higher than 104 - Fahrenheit, The Nation learnt on Thursday. The treatment of the disease is very expensive even a single injection in the treatment has worth of Rs 0.2 million. Pakistan Medical Association (PMA), Karachi Chapter warned the citizens to be aware of such fatal disease and demanded the government to bring some changes in visas policies to protect our country from those people who suffers with fatal diseases, which are not common in the country. It is pertinent to mention here that Kawasaki disease is diagnosed in 19 out of every 100,000 children, which is most common among children of Japanese and Korean descent, but can affect all ethnic groups. As per Kids Health Organisation (KHO), Kawasaki disease is an illness that involves the skin, mouth, and lymph nodes, and most often affects kids under age 5 years. The cause is unknown, but if the symptoms are recognised early, kids with Kawasaki disease can fully recover within a few days but if remain untreated, leads to serious complications that can affect the heart. According to sources at the AKUH, a patient, Taha (7), was rushed to the hospital last Sunday with symptoms of high fever. He was undergoing persistent fever for the last 10 days. According to the experts, no test can detect Kawasaki disease, so doctors usually diagnose it by evaluating the symptoms. Most kids diagnosed with Kawasaki disease will have a fever lasting 5 or more days and at least four of these symptoms including redness in eyes, changes around the lips, tongue, or mouth, changes in the fingers and toes, such as swelling, discoloration, or peeling, a rash on genital organs, a large swollen lymph node in the neck, red and swollen palms of hands and soles of feet. If Kawasaki disease is suspected, the doctor may order tests to monitor heart function and might take blood and urine samples to rule out other conditions. Kawasaki disease can't be prevented but usually has telltale symptoms and signs that appear in phases. The first phase, which can last for up to 2 weeks, usually involves a persistent fever higher than 104_ Fahrenheit (39 Celsius) and lasts for at least 5 days. Doctors can manage the symptoms of Kawasaki disease if they catch it early. Symptoms often disappear within just 2 days of the start of treatment. If Kawasaki disease is treated within 10 days of the onset of symptoms, heart problems usually do not develop. Treatment should begin as soon as possible, ideally within 10 days of when the fever begins. Usually, a child is treated with intravenous doses of gamma globulin (purified antibodies), an ingredient of blood that helps the body fight infection. The child also might be given a high dose of aspirin to reduce the risk of heart problems." According to Wikipedia encyclopedia, the cardiac complications are, by far, the most important aspect of the disease. Kawasaki disease can cause vasculitic changes (inflammation of blood vessels) in the coronary arteries and subsequent coronary artery aneurysms. These aneurysms can lead to myocardial infarction (heart attack) even in young children. Overall, about 10-18 per cent of children with Kawasaki disease develop coronary artery aneurysms Kawasaki syndrome and risk factors for coronary artery abnormalities. Commenting on the issue, Secretary PMA Dr Samrina Hashmi said that it was fortunate that the disease was not infectious, while the citizens should be aware of the fatality of the disease. She said that the treatment of the disease was very expensive, which unaffordable for poor families. In this regard, the government should take concrete measures to provide treatment facilities at government hospitals. She demanded the government to take some important changes in our visa policies so that such type of diseases could not be imported into the country.