ISLAMABAD - Pakistan on Saturday lodged strong protest with the United States against the drone attacks saying the missile strikes on tribal areas constituted infringement of Pakistan's sovereignty. President Asif Ali Zardari, in meeting here with US Ambassador to Pakistan Anne W Patterson, expressed grave concern over the drone strikes by the United States on tribal areas. According to officials privy to the meeting, the President cautioned the Obama administration that drone attacks could harm the cooperation between Islamabad and Washington in war on terror. He said that only Pakistani security forces could take action against the militants on the country's soil, an official said requesting anonymity. He said the President, however, hoped that the new US administration would reverse the policy adopted by the previous US government and stop the drone attacks. Meanwhile, the Foreign Office spokesman Muhammad Sadiq also expressed Pakistan's concern over the US missile strikes in the tribal region. "Pakistan has consistently lodged strong protest with the US government against the drone attacks, which constitute infringement of Pakistan's sovereignty," he said. "Yesterday's attack in the Waziristan area which caused civilian causalities is a matter of great concern. These concerns have been conveyed to the US side," he said. "With the advent of the new US administration it is Pakistan's sincere hope that the United States will review its policy and adopt a more holistic and integrated approach towards dealing with the issue of terrorism and extremism," Sadiq said. "We maintain that these attacks are counter-productive and should be discontinued. Pakistan urges the USA and NATO to adopt a holistic and more effective approach to countering extremism and terrorism," he said. In response to a question, the spokesman confirmed that Foreign Minister Shah Mahmood Qureshi had written a letter to Ambassador Richard Holbrooke, the newly appointed US Special Representative to the region. The Foreign Minister, while congratulating him on his appointment, invited Ambassador Holbrooke to visit Islamabad for exchanging views and charting a trajectory of cooperation between the region and the US in the days ahead, he said. In reply to another question, the spokesman said Pakistan welcomed the US administration's decision to close down the Guantanamo Bay Detention Center. "Pakistan is confident that the new US administration will develop a holistic strategy in successfully overcoming the complex challenges confronting the world today," Sadiq added. He further said that closing Guantanamo Bay Detention Centers signaled an important step towards upholding the primacy of the rule of law and added the much-needed moral dimension in dealing with terrorism.